The Double Marker Test is a crucial prenatal screening performed during the first trimester of pregnancy, typically between the 11th and 14th weeks. It evaluates the levels of two specific substances in the mother’s blood—free Beta hCG and PAPP-A (Pregnancy-Associated Plasma Protein A)—to assess the risk of chromosomal abnormalities in the fetus, such as Down syndrome (Trisomy 21), Trisomy 18, and Trisomy 13. Often recommended for women above the age of 35 or those with a family history of genetic conditions, this non-invasive test helps doctors make informed decisions about further diagnostic procedures. When combined with an ultrasound (NT scan), the Double Marker Test offers more accurate results, ensuring better prenatal care and peace of mind for expecting parents.