The HLA B27 Test is a blood test used to detect the presence of the HLA-B27 protein on the surface of white blood cells. This genetic marker is associated with a higher risk of developing certain autoimmune conditions, such as ankylosing spondylitis, reactive arthritis, and other related inflammatory diseases. While a positive HLA B27 result does not confirm a specific diagnosis, it helps doctors piece together clinical symptoms and other test results for a more accurate evaluation. The test is typically recommended if you are experiencing chronic joint pain, stiffness, or inflammation. Early detection through the HLA B27 test can guide better management and treatment plans to improve quality of life.